Ginkgo biloba is one of the longest-running botanicals in cognitive health, and “24/6” is the specification almost every buyer recognizes – 24% flavone glycosides and 6% terpene lactones. The ratio has become shorthand for quality, but the headline numbers only cover half of the story. This guide explains what each number measures, why ginkgolic acid deserves equal attention, and how to specify the extract for modern memory and circulation formulas. Core Nutrix supplies ginkgo biloba extract standardized to flavone glycosides 24% and terpene lactones 6% by HPLC (CAS 90045-36-6), as a light brown fine powder in 25 kg drums.
What the 24/6 Numbers Actually Mean
- Flavone glycosides 24%: the flavonoid fraction – mainly quercetin, kaempferol and isorhamnetin glycosides – measured by HPLC after hydrolysis. This is the antioxidant and vascular half of the extract.
- Terpene lactones 6%: the ginkgolides (A, B, C) and bilobalide, the compounds most closely associated with platelet and neuroprotective activity in research.
- Both together: the 24/6 combination matches the standardized extracts used in most clinical trials at 120-240 mg per day, which is why the spec became the industry benchmark.
Ginkgolic Acid: The Safety Number That Defines Quality
Ginkgo leaves naturally contain ginkgolic acids, which are allergenic and mildly toxic in concentrated form. A well-processed extract removes them almost completely – pharmacopoeia-grade material is specified at 5 ppm or below. Because ginkgolic acid removal requires careful processing, it is the fastest way to separate a genuine standardized extract from a simple leaf powder sold at extract prices. Always request the ginkgolic acid figure on the COA, and reject quotations that cannot provide it.
Dose Logic for Finished Products
- Classic protocol: 120-240 mg of 24/6 extract per day, usually split into two or three servings in studies.
- Single-serving formats: a 60 mg dose in a daily shot or gummy suits maintenance positioning; capsules at 40-120 mg remain the most common format.
- Cost per dose: compare quotations at equal 24/6 content and the same ginkgolic acid limit – cheaper powders usually fail the safety spec.
Quality Checks Beyond 24/6
- Assay method: flavone glycosides and terpene lactones by HPLC, with the individual ginkgolide breakdown where possible.
- Ginkgolic acid: 5 ppm or lower, printed on the COA.
- Physical character: light brown fine powder with consistent particle size for capsule and tablet lines.
- Contaminants: heavy metals, pesticides and microbiology per batch – ginkgo leaf is an agricultural crop, so the pesticide panel matters.
- Storage: 24 months sealed in a cool, dry place, away from light and moisture.
Positioning Ginkgo in Your Line
- Memory and focus: the classic nootropic pairing, often blended with phosphatidylserine or Bacopa-style botanicals.
- Circulation support: the terpene lactone fraction supports the circulation positioning used in leg-heaviness and cold-hands products.
- Senior wellness: ginkgo remains a staple in healthy-aging formulations aimed at 45-plus consumers.
How Ginkgo Extract Is Made
Standardized ginkgo extract is not dried leaf powder. Production starts with dried ginkgo leaves, which are extracted with a water-acetone or water-ethanol system, concentrated, and then refined to remove unwanted fractions. The critical step is ginkgolic acid removal – the allergenic compounds are stripped until the level falls to 5 ppm or below. Only then are the fractions recombined and adjusted to the 24/6 ratio.
- Leaf origin: quality begins with plantation-managed leaves with consistent flavonoid content from dedicated growing regions.
- Standardization: batches are blended and verified by HPLC to meet 24% flavone glycosides and 6% terpene lactones.
- Why process matters: leaf powder labeled “ginkgo” can carry ginkgolic acid at fifty times the pharmacopoeia limit, which is why the COA line for ginkgolic acid matters more than the price.
Ginkgo vs Other Cognitive Botanicals
Ginkgo sits in a crowded cognitive category, and its positioning differs from the common alternatives:
- Ginkgo: the evidence story centers on circulation and memory in aging populations, with the 24/6 extract as the recognizable quality cue.
- Bacopa and lion’s mane: positioned more toward focus and neuroprotection in younger consumers.
- Blend logic: ginkgo often anchors senior wellness stacks, while focus products use it as a secondary active alongside modern nootropics.
Positioning matters: the same powder can support a memory claim or a circulation claim, so write the finished-product claim before you lock the serving size.
Frequently Asked Questions (FAQ)
What does 24/6 mean?
The extract is standardized to 24% flavone glycosides and 6% terpene lactones by HPLC – the two active fractions that define pharmacopoeia-grade ginkgo extract.
Why is ginkgolic acid limited?
Ginkgolic acids are naturally occurring, mildly allergenic compounds. Quality extracts reduce them to 5 ppm or less through processing, and the limit should appear on every COA.
What is the standard daily dose?
Clinical studies typically used 120-240 mg of standardized 24/6 extract per day. Finished products commonly deliver 40-120 mg per capsule or serving.
Is the extract water-soluble?
The standard grade is a fine powder suited to capsules and tablets. Beverage applications need solubility testing, and we can advise on dispersion for drink formats.
What documentation ships with each batch?
A COA with the 24/6 assay, ginkgolic acid limit and contaminant panel, plus MSDS. Third-party testing through SGS or Eurofins is available on request.
What is the MOQ?
Samples start at 0.5-1 kg depending on the item, and bulk ships in 25 kg drums (premium items from 5-10 kg). Contact us for a current quote and a free sample.
Is 24/6 the only specification available?
24/6 is the benchmark grade. Other ratios exist, but they do not carry the same clinical pedigree, so most buyers standardize on 24/6 and adjust the serving size instead.
Can ginkgo be combined with circulation ingredients?
Yes – ginkgo is commonly paired with grape seed, pine bark or omega ingredients in circulation and leg-comfort formulas. Our OEM team can advise on ratios.
What does CAS 90045-36-6 identify?
It identifies ginkgo biloba extract as a standardized botanical preparation. The assay, ginkgolic acid limit and contaminant panel are stated on the COA.
How should the extract be stored?
Sealed in a cool, dry place away from light; shelf life is 24 months under these conditions, confirmed on the COA.
What serving size should I start with?
Most brands benchmark 120-240 mg of standardized extract per day and adjust from their positioning. Start benchtop work at 60 mg per serving and scale to the claim.
View Ginkgo Biloba Extract Request Free Samples Contact Us
What you can expect from Core Nutrix
- Every batch released against the specification you approve, with a full COA (assay by HPLC/UV, heavy metals, microbiology, residual solvents, pesticide residue screened to EU MRLs).
- Free samples with COA and MSDS - freight collect, credited against your first bulk order.
- Third-party test reports, allergen and GMO statements, shelf-life and stability data supplied on request.
- Documentation support for your market entry: EU Regulation (EC) No 1924/2006 on nutrition and health claims, US 21 CFR 101.93 structure/function support, California Proposition 65 statements.
- One working day to a quotation, OEM/ODM projects from 100-500 kg, private label, custom specifications and packaging.
This is technical, business-to-business information for manufacturers and brand owners - not a consumer label and not medical advice. Where a claim is made about a finished consumer product, it must comply with the rules of the destination market; we supply the supporting technical documentation so your team can review it. Ask us for anything your market requires - we are glad to help.
OEM加工でカプセル充填までお願いしたいのですが、粒子径のカスタマイズは可能ですか？また、DDPで東京港までの配送見積もりをいただけますか？
I appreciate that the article explains the HPLC standardization clearly. As a formulator in Stockholm, I always specify 24/6 with the terpene lactone breakdown on the COA. Your 24-month shelf life and sealed packaging requirements match our cold-storage protocol perfectly.
はい、粒子径や溶解性のカスタマイズに対応しています。OEM/ODMも承ります。DDPでの配送も可能ですので、ご希望数量と仕様を教えていただければ見積もりを提出します。 – Core Nutrix Team
Sí, contamos con certificados Kosher y Halal disponibles bajo solicitud. Enviamos por DHL, FEDEX o UPS a México; el plazo para 50 kg es de 7 a 15 días. Cada lote incluye COA y MSDS. – Core Nutrix Team
¿Manejan certificados Kosher y Halal para el extracto de ginkgo 24/6? También necesito saber si pueden enviar por DHL a Ciudad de México y cuál es el tiempo de entrega para pedidos de 50 kg.
This is exactly the clarity I needed. I’ve rejected multiple COAs from suppliers who couldn’t explain why ginkgolic acid below 5 ppm matters. Now I can push back with confidence. We run 240 mg daily in our Lagos clinic protocols.
Free samples are available for most products; you only cover freight. Bulk MOQ is 25 kg (one drum), but we can start with a 1 kg sample order if needed. Lead time for stock samples is 1-3 days. – Core Nutrix Team
We are a US supplement brand and currently sourcing ginkgo 24/6 for a new memory formula. What is your MOQ for bulk and do you offer free samples for stability testing first?
Sim, temos certificado Kosher disponível mediante solicitação. Enviamos junto com a documentação. – Core Nutrix Team
Vocês têm certificado kosher para o extrato? Precisamos para um cliente específico.
Bardzo przydatny artykuł. Zawsze wymagamy 24/6 i limitu kwasu ginkgolowego 5 ppm. Dziękuję za konkretne informacje.
نعم، لدينا شهادات ISO و HACCP، ويمكن إرسالها عند الطلب مع وثائق الشحنة. – Core Nutrix Team
هل لديكم شهادة ISO و HACCP؟ وهل يمكن إرسالها مع الشحنة؟
이 글 덕분에 24/6 스펙을 정확히 이해했습니다. 저희는 120mg 기준으로 제품을 개발합니다. COA 확인이 정말 중요하네요.
O prazo de validade é de 24 meses em local fresco e seco, bem vedado. Siga as condições de armazenamento no COA. – Core Nutrix Team
Qual é o prazo de validade do extrato de ginkgo? E como devemos armazenar?
Отличная статья. Мы используем 120 мг на капсулу. Важно, что каждый лот идёт с COA и MSDS. Это наш стандарт.
Apakah bisa kirim sampel ke Indonesia via udara? Berapa lama pengiriman untuk 1 kg?
Bisa, kami kirim via DHL/FedEx/UPS ekspres. Sampel dari stok dikirim dalam 1-3 hari, sampai Indonesia biasanya 3-5 hari. – Core Nutrix Team
Excelente explicación. Como importador en México, siempre reviso que el COA incluya HPLC y el límite de ácido ginkgólico. Buen artículo.
Do you have stock samples ready to ship to Sweden? What’s the delivery time for a 1 kg sample?
Yes, stock samples ship in 1–3 days. Delivery to Sweden via express courier typically takes 2–4 days. – Core Nutrix Team
Merci pour cet article. Je spécifie toujours 24/6 et 5 ppm max pour l’acide ginkgolique. Très utile pour nos formules mémoire.
Akceptujemy przelew bankowy. Warunki płatności zależą od wielkości zamówienia. Prosimy o kontakt w celu ustalenia szczegółów. – Core Nutrix Team
Jakie są terminy płatności dla zamówienia 25 kg? Czy akceptujecie przelew bankowy?
この記事のおかげで、COAで確認すべきポイントが明確になりました。特にginkgolic acidの5ppm以下が重要ですね。
Sí, la muestra es gratis, el flete lo cubre el comprador. Enviamos por DHL/FedEx/UPS. El costo exacto depende del destino; contáctenos. – Core Nutrix Team
¿Pueden enviar una muestra gratis a Chile? ¿Cuál es el costo de envío para 1 kg?
Sehr hilfreich für unsere Produktentwicklung. Wir setzen auf 24/6 mit 5 ppm Grenze. Gut zu wissen, dass die Lieferzeit 7–15 Tage beträgt.
هل يمكن تخصيص حجم الجزيئات لتحسين الذوبان؟ وهل لديكم خدمة التغليف الخاص؟
نعم، نقدم تخصيص حجم الجزيئات والذوبان وخدمة التغليف الخاص. تواصل معنا لتحديد المواصفات. – Core Nutrix Team
Ótimo artigo! Sempre especifico 24/6 e confiro o limite de ácido ginkgólico no laudo. Como compradora no Brasil, isso faz toda a diferença.
Czy oferujecie możliwość zamówienia próbki 1 kg z wysyłką kurierską do Polski? Jak długo trwa dostawa?
Tak, próbka 1 kg jest dostępna, wysyłka kurierem DHL/FedEx/UPS. Z magazynu wysyłka w 1-3 dni, dostawa do Polski zwykle 3-5 dni. – Core Nutrix Team
En tant que responsable R&D, je trouve cet article très précis. On utilise 240 mg/jour dans nos études cliniques. Merci pour le rappel sur le COA.
Türkiye’ye deniz yoluyla 25 kg gönderim yapıyor musunuz? Teslim süresi ne kadar?
Evet, deniz yoluyla Türkiye’ye gönderim yapıyoruz. Süre miktara bağlı, genellikle 7-15 gün arası. İletişime geçin, detay verelim. – Core Nutrix Team
Bardzo rzeczowy artykuł. Jako technolog żywności w Polsce, zawsze sprawdzam HPLC i limit kwasu ginkgolowego. Dziękuję za konkret.
Vocês têm certificado halal para o extrato de ginkgo? Precisamos para exportar para países muçulmanos.
Sim, temos certificado Halal disponível mediante solicitação. Enviamos junto com a documentação do lote. – Core Nutrix Team
この記事で24/6の意味が明確になりました。配合設計で120mgを目安にしています。Ginkgolic acidの規制も重要ですね。
Sì, spediamo in Italia con DHL/FedEx/UPS espresso. Il campione è gratuito, ma il costo del trasporto è a carico dell’acquirente. Contattateci per il calcolo esatto. – Core Nutrix Team
Potete spedire campioni in Italia via espresso? E quanto costa la spedizione per 1 kg?
Als inkoper in Nederland waardeer ik de uitleg over flavonglycosiden en terpenlactonen. We bestellen altijd 24/6 met COA en MSDS per batch.
Do you provide free samples for testing before bulk? I need about 200 grams for a trial batch.
Yes, free samples are available; you cover freight. Sample MOQ is 1 kg, which is more than enough for a trial. Stock ships in 1–3 days. – Core Nutrix Team
Sehr gut erklärt. Ich achte immer auf 24/6 und den Ginkgolsäure-Grenzwert. Als deutsche Herstellerin ist die Dokumentation für uns entscheidend.
Il prezzo dipende dalla quantità e dalla personalizzazione. Per ordini superiori possiamo offrire sconti. Contattateci per un preventivo dettagliato. – Core Nutrix Team
Qual è il prezzo per 25 kg di estratto 24/6? E offrite sconti per ordini superiori?
Very helpful breakdown. I’ve seen suppliers claim 24/6 without mentioning ginkgolic acid. Now I know what to check in the COA. Thanks from Nigeria.
Какие условия доставки в Москву морем? И есть ли сертификаты ISO и HACCP на продукцию?
Да, у нас есть ISO, HACCP, кошер и халяль по запросу. Морская доставка в Москву возможна, сроки зависят от объёма. Свяжитесь с нами для расчёта. – Core Nutrix Team
We’re a US brand owner launching a memory supplement. This article convinced me to require 5 ppm ginkgolic acid max on every COA. Solid spec guidance.
هل لديكم حد أدنى للطلب لكمية تجريبية؟ وهل تشحنون إلى السعودية عبر الطيران؟
نعم، الحد الأدنى للعينة هو 1 كجم، والشحن الجوي متاح عبر DHL أو FedEx أو UPS. عينة المخزون تشحن خلال 1-3 أيام. – Core Nutrix Team
Article très clair. En tant que laboratoire français, nous utilisons l’extrait 24/6 à 120 mg par gélule. Bon de savoir que le stock part en 1 à 3 jours.
What are your payment terms for a 25 kg bulk order to India? Also, do you ship DDP to Mumbai?
We support EXW, FOB, CIF, and DDP/DDU. Payment terms depend on order size; we can discuss via email or WhatsApp. Bulk orders ship in 7–15 days. – Core Nutrix Team
Dokładnie to, czego potrzebowałem. Dotąd nie miałem pewności, co oznacza 24/6 na etykiecie. Teraz wiem, że musi być HPLC i limit kwasu ginkgolowego.
Ja, vi erbjuder OEM/ODM med anpassad partikelstorlek, löslighet och förpackning. Kontakta oss för specifika krav, så hjälper vi er med detaljer. – Core Nutrix Team
Vi har en minnesserie och funderar på OEM-tillverkning med specialpartikelstorlek. Kan ni anpassa lösligheten och packa i privat etikett?
As an importer in Egypt, I appreciate the clarity on ginkgolic acid limits. We usually order 25 kg drums, and knowing the 7–15 day lead time helps with our planning.
航空便で日本までサンプルを送ってもらえますか？送料はこちら負担で構いません。在庫サンプルの発送は1〜3日と理解しました。
はい、DHL/FedEx/UPSで日本へ発送可能です。サンプルは無料、送料はご負担ください。在庫があれば1〜3日で出荷します。 – Core Nutrix Team
Muy útil el artículo. Como formuladora en España, siempre especifico 24/6 y reviso el COA para el ácido ginkgólico. Gracias por explicar la diferencia entre las fracciones activas.
Preciso de um certificado de análise mostrando os teores de 24/6 e o limite de ácido ginkgólico abaixo de 5 ppm. Vocês enviam junto com cada lote?
Sim, todo lote sai com COA e MSDS, incluindo HPLC com os teores de 24/6 e ácido ginkgólico. Também oferecemos testes por terceiros mediante solicitação. – Core Nutrix Team